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CD247 / CD3 Zeta

CD247 molecule

CD247 / CD3 Zeta is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: CD247 molecule
Synonyms: CD247, CD3 Zeta, CD3H, CD3Z, CD247 antigen, zeta subunit, CD247 molecule, CD3zeta chain, T3Z, TCR zeta chain, TCRZ, T-cell receptor T3 zeta chain, CD247 antigen, CD3-ZETA, CD3Q
Target Sequences: NM_000734 NP_000725.1 P20963

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
CD247 / CD3 Zeta (11)
No (11)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (2)
Myc-DDK (Flag) (6)
Human (8)
Mouse (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
CD247 / CD3 Zeta Protein - Purified recombinant protein CD247 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
16.3 kDa
20 µg/$1,107
CD247 / CD3 Zeta Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
CD247 / CD3 Zeta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
18.7 kDa
20 µg/$150
CD247 / CD3 Zeta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.3 kDa
20 µg/$150
CD247 / CD3 Zeta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.3 kDa
100 µg/$494
CD247 / CD3 Zeta Protein - Purified recombinant protein CD247 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
16.2 kDa
20 µg/$1,107
Select
E. coli
GST, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.1
100 µg/$235; 20 µg/$205
CD247 / CD3 Zeta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.7 kDa
100 µg/$494
CD247 / CD3 Zeta Protein - 12.5% SDS-PAGE of human CD3Z stained with Coomassie Blue
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Wheat Germ Extract
GST
43.78 kDa
10 µg/$479; 25 µg/$670
CD247 / CD3 Zeta Protein - Recombinant Cluster Of Differentiation 247 (CD247) by SDS-PAGE
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E. coli
His, N-Terminal
19.9kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CD247 / CD3 Zeta Protein - Recombinant Cluster Of Differentiation 247 (CD247) by SDS-PAGE
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E. coli
His, N-Terminal
19.4kDa
10 µg/$286; 50 µg/$472; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,761
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).