Human SCG3 / Secretogranin 3

Rabbit

Human (tested or 100% immunogen sequence identity)

Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit, Sheep (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of human Secretogranin 3 (DFINKQADAYVEK, aa438-450 of UniProt Q8WXD2). Percent identity by BLAST analysis: Human (100%); Mouse, Rat, Ferret, Sheep, Cat, Bovine, Hamster, Rabbit, Pig, Dog (92%); Horse, Opossum, Xenopus (85%).

aa438-450

Human SCG3 / Secretogranin 3

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• IHC - Frozen (0.5 - 1 µg/ml)
• ICC (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)

SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q8WXD2 NCBI: NM_013243 NP_037375.2