Target
Human PRG2 / Proteoglycan 2
Synonyms
PRG2 | BMPG | Bone marrow proteoglycan | Bone-marrow proteoglycan | Eosinophil major basic protein | MBP1 | Natural killer cell activator | Proteoglycan 2 | Proteoglycan 2 preproprotein
Reactivity
Human
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat, Horse
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Immunogen
Major Basic Protein.
Specificity
Specific for human eosinophil major basic protein (14kD) irrespective of the stages of eosinophil activation and can be regarded as a 'pan-eosinophil' marker. Recognizes secreted pro-form of MBP (Pregnancy associated MBP, 23.8kD) and mature form found in the matrix of the eosinophil large specific granule (13.8kD). Does not cross-react with equine, mouse or rat MBP.
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- Western blot
- ELISA
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Usage
Suitable for use in Immunohistochemistry, Western Blot and ELISA. Immunohistochemistry: Fresh frozen (methanol: acetone). Immunohistochemistry: Formalin fixed paraffin-embedded. (treat with 0.1% trypsin before blocking). The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 1 mg/ml BSA. No preservative added.
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PRG2 / Proteoglycan 2