Target
Human EMA / MUC1
Synonyms
MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Phycoerythrin.
Also available
Unconjugated or conjugated with
APC,
Biotin,
FITC,
HRP.
Immunogen
High molecular weight (>300kDa) glycoprotein from human milk-fat globule molecule.
Specificity
Binds with high efficiency to an epitope within the VNTR recombinant repeat peptide region of MUC1 molecule. Reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (but not with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1, but not with completely glycosylated MUC1. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross-reactive with normal serum proteins and human tissues of nonepithelial origin.